You are delivering a presentation and the audience members are busy sending updates on Twitter or Facebook using their smartphones. Here’s how you should deal with such a situations:
Create Twitter-friendly messages. Create up to four Twitter-friendly messages that you would want your audience to post to their followers. Speakers stand a better chance of getting these ideas in the Twitter stream by building slides using the key messages as the title.
Take breaks. Atkinson recommends that you take a break from the slides and bring up your Twitter stream during your presentation, addressing questions and comments that your audience is posting. Atkinson suggests taking up to three breaks, but of course this depends on the activity of the event. link.