Snitter, Spaz and Twhirl are pretty good desktop clients for Twitter - all of them use the Adobe AIR platform and can therefore run on Mac and Windows.
They are all very similar in features but if I were to pick one of the three, I would probably go with Twhirl - it sports the most elegant interface of them all and you can add multiple Twitter accounts.
Hover the mouse over the avatars of your Twitter friends and you get access to various options like direct messages, replies, etc.
And Twhirl is probably the only Twitter client that lets me change the font of tweets. Thanks Tamar.
Find this article at: http://www.labnol.org/software/download/best-twitter-client-software-windows/2135/
web: http://www.labnol.org/ email: amit@labnol.org


Reader Comments
Snitter is an HTML app, so you can use the User Styles screen to apply any CSS to the interface. To change the font, you can add something like this:
.tweettext {
font-family:”Calibri”;
font-size:16px;
line-height:1.2;
}
Thanks for the mention!
Written by Jonathan Snook on 01.24.08
I’ve used Snitter and feel it has a very cool and friendly user interface. Now I am going to check Thwirl based on your recommendations.
Written by Syahid A. on 01.24.08
Adobe Air didn’t play nice on my win xp machine. Installed it but when I tried to install the programs I got the blue screen of death. After 3 blues, uninstalled! boo adobe air.
Written by Rob Williams on 01.24.08
I really liked Snitter. However my issue is with any Adobe Air application - if i leave one running for a few days on my laptop, it continuously consumes RAM/Virtual Memory with no end in sight!
Written by Ram H. Viswanathan on 01.24.08
I’m a big Twhirl fan, I use it on both my macbook and dell laptop. If you’re following over 500 friends on twitter it works great vs other twitter apps that hangs when trying to pull down tweets. You can also follow and communicate with the Twhirl developer on twitter his id is twitter.com/twhirl and mine is twitter.com/waynesutton
Written by Wayne Sutton on 01.25.08
What about Twitteroo?
Written by Carro Brasilia on 11.20.08
I’m also not a big fan of Adobe AIR. I uninstalled it after it caused problems on my Windows XP machine. I prefer using software that doesn’t rely on other software to work.
Written by Steve Atwal on 12.20.08
I am glad I am not the only one having issues with adobe air, Now I have been using a program not mentioned here called “tweetdeck” and it also uses adobe air and I find the longer I have adobe air running the slower everything else on my machine gets :( I love the apps but can’t stand the side effects
Written by Carl Breed on 01.21.09
I was using Tweetdeck also when it stopped working correctly on my machine. I finally tried to uninstall and reinstall and keep getting conflicting messages about Adobe Air. Tweetdeck installation says I need that to complete install but try to install Adobe Air and get a message that it is already installed.
So I won’t be using anything with Adobe Air.
Written by Nicole Bandes on 02.11.09
I would never use an Adobe Air-based app. An app that needs access to your entire file system with access to the internet as well? You’ve just created a hole straight through your firewall - lunacy!
Written by Darren on 02.14.09
tweetdeck is my favourite: link .
I tend to keep an eye on what Stephen Fry is using to post, that how I found tweetdeck
Written by captaininbox on 02.14.09
The best one is M.twitter.com. Not laggy and it works on your cellphones :)
Written by ant on 03.04.09